I don't really keep-up with podcasts, or lately, my RSS feeds and friends list, but when I have taken the time to catch up on a couple of podcasts, I find two music-related podcasts compelling tonics to the general pap of modern music:

NPR's All Songs Considered.

Bob Boilen directs All Things Considered. As part of the show, he's responsible for the bumps between stories NPR calls "Musical Interludes." He's also the host of the podcast/streaming only NPR show, All Songs Considered. The show has two sides. First, a generally weekly podcast that Boilen curates more than anything. In roughly half-an-hour, he'll run through six or seven songs, talk about what an artist is doing and why he's putting it in the show.